What are the possible side effects of sulfasalazine?

If you experience any of the following serious side effects, stop taking sulfasalazine and seek emergency medical attention or notify your doctor immediately:an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); orworsening colitis (fever, abdominal pain, cramping, or bloody diarrhea); orsore throat, fever, pale skin, bruising, or yellow skin or eyes (may indicate a blood disorder).

Other, less serious side effects may be more likely to occur. Continue to take sulfasalazine and talk to your doctor if you experience

nausea, vomiting, or decreased appetite;headache;a rash, itching, or hives;fever;decreased sperm production (uncommon and usually reversible); ororange-yellow discoloration of the skin or urine (not harmful).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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