Anagrelide lowers the number of blood clotting cells (called platelets) in the body. This helps to prevent blood clots from forming.
Anagrelide is used to treat essential thrombocytosis (too many blood clotting cells in the body).
Anagrelide may also be used for purposes other than those listed in this medication guide.
Before taking anagrelide, tell your doctor if you have
heart disease,kidney disease, orliver disease.
You may not be able to take anagrelide, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Anagrelide is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.It is not known whether anagrelide passes into breast milk. Do not take this medication without first talking to your doctor if you are breast feeding a baby.
Anagrelide is not approved for use by children younger than 16 years old.
If you experience any of the following serious side effects, stop taking anagrelide and seek emergency medical attention or notify your doctor immediately:an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);fast, slow, or irregular heartbeat;chest pain;swelling of the hands, feet, or legs;shortness of breath or difficulty in breathing;seizures;bloody or black vomit or stools;abdominal pain;unusual, prolonged, or severe bleeding or bruising; ora bleeding nose.
Other, less serious side effects may also occur. Continue to take anagrelide and talk to your doctor if you experience
headache;diarrhea; tingling or numbness in the hands or feet;upset stomach, nausea, or vomiting;dizziness;gas;fever;a rash or itching;loss of appetite;sore throat;cough; orback pain.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Tell your doctor and dentist that you are taking this medication before undergoing any surgical procedures.
Your doctor will need to monitor your blood with blood tests before starting treatment with anagrelide, every 2 days for the first week of treatment, and at least weekly thereafter until the desired maintenance dosage is reached.
Take anagrelide exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Your doctor will need to monitor your blood with blood tests before starting treatment with anagrelide, every 2 days for the first week of treatment, and at least weekly thereafter until the desired maintenance dosage is reached.
Store anagrelide at room temperature away from moisture and heat.
There are no known interactions between anagrelide and other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Some forms of this medication are made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
Other drugs that affect bleeding or blood-clotting may interact with antihemophilic factor (factor VIII) and cause dangerous side effects or make the medicine less effective.
There may be other drugs that can affect antihemophilic factor (factor VIII). Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
There are no restrictions on food, beverages, or activity while using this medication unless your doctor has told you otherwise.
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